It is now understood that that poor thorax biomechanics can play a role in multiple conditions and at regions far removed from it. This article describes the Integrated Systems Model approach for holistic assessment and treatment of your patients and a case study demonstrates how it can be used to identify the previously unsuspected (and, therefore, untreated) involvement of the thorax in a recurrent hamstring injury. Understanding and applying this biopsychosocial approach will enable you to find all the drivers of your patient’s injury and treat them in a meaningful way, so allowing your patient to get back to doing what they love. This article has been extracted from the author’s book The Thorax – An Integrated Approach. Register free below (or log in if you already have an account) and you can access the article key points, the downloadable template of the Clinical Puzzle and other related resources.